The statement expresses concerns regarding Iran’s non-cooperation with the IAEA and the production of highly enriched uranium, and Syria’s undeclared nuclear activities. The statement reiterates the US commitment to establishing a WMDFZ in the Middle East. It acknowledges the positive role of the UN Conference in establishing the zone yet questions its effectiveness in convening a direct dialogue among all the regional states. US non-participation in the conference does not impede the implementation of the 1995 resolution.